Curran Laboratory
Michael A. Curran, Ph.D.
Principal Investigator
- Departments, Labs and Institutes
- Labs
- Curran Laboratory
Areas of Research
- Immunology
- Immunotherapy
Despite the success of immunotherapy in melanoma, many immunologically ¡°cold¡± tumors, such as prostate and pancreatic cancer, fail to respond to checkpoint blockade. Research in the Curran Laboratory focuses on discovering mechanisms by which these immune-resistant cancers evade the host T cell response and resist checkpoint antibody therapy. Companion translational studies investigate immunologic and metabolic interventions designed to reverse microenvironmental immune suppression and re-sensitize these cancers to host immunity.
Meet the Team
September 2018, from left to right: Anu Srinivasamani, Priya Jayaprakash, Ravaen Slay, Akash Boda, Casey Ager, Mike Curran, Meghan Dean, Gen Hartley, Alex Chen, Rishika Prasad, Arthur Liu, Brittany Charleton