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Publications

. Intensity modulated proton arc therapy via geometry-based energy selection for ependymoma. J Appl Clin Med Phys:e13954. e-Pub 2023. PMID: 36913484.
. Cognitive Sparing in Proton versus Photon Radiotherapy for Pediatric Brain Tumor Is Associated with White Matter Integrity: An Exploratory Study. Cancers (Basel) 15(6), 2023. e-Pub 2023. PMID: 36980730.
. Response assessment in pediatric craniopharyngioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group. Neuro Oncol 25(2):224-233, 2023. e-Pub 2022. PMID: 36124689.
. Late Effects of Craniospinal Irradiation Using Electron Spinal Fields for Pediatric Cancer Patients. Int J Radiat Oncol Biol Phys 115(1):164-173, 2023. e-Pub 2022. PMID: 35716848.
Chevli N, Grosshans DR, McAleer MF, Foster JH, Harrison D, McGovern SL, Paulino AC. Renal function in abdominal neuroblastoma patients undergoing proton radiotherapy. Pediatric Blood & Cancer 70(1):e29981, 2023. e-Pub 2022. PMID: 36129239.
. A Prospective Study of Conventionally Fractionated Dose Constraints for Re-Irradiation of Primary Brain Tumors in Adults. Pract Radiat Oncol. e-Pub 2022. PMID: 36596356.
. A Prospective Evaluation of Fatigue in Pediatric Brain Tumor Patients Treated With Radiation Therapy. J Pediatr Hematol Oncol Nurs 39(6):358-365, 2022. e-Pub 2022. PMID: 36285825.
. Looking on the horizon; potential and unique approaches to developing radiation countermeasures for deep space travel. Life Sci Space Res (Amst) 35:105-112, 2022. e-Pub 2022. PMID: 36336356.
. Targeting hippocampal neurogenesis to protect astronauts' cognition and mood from decline due to space radiation effects. Life Sci Space Res (Amst) 35:170-179, 2022. e-Pub 2022. PMID: 36336363.
. Interventions for preventing and ameliorating cognitive deficits in adults treated with cranial irradiation. Cochrane Database Syst Rev 11(11):CD011335, 2022. e-Pub 2022. PMID: 36427235.
. Immune Checkpoint Inhibitors Have Clinical Activity in Patients With Recurrent Chordoma. J Immunother 45(8):374-378, 2022. e-Pub 2022. PMID: 35943386.
. Quantifying the risk and dosimetric variables of symptomatic brainstem injury after proton beam radiation in pediatric brain tumors. Neuro Oncol 24(9):1571-1581, 2022. e-Pub 2022. PMID: 35157767.
. Predicting neurocognitive function in pediatric brain tumor early survivorship: The neurological predictor scale and the incremental validity of tumor size. Pediatr Blood Cancer 69(9):e29803, 2022. e-Pub 2022. PMID: 35709014.
. Roadmap: helium ion therapy. Phys Med Biol 67(15), 2022. e-Pub 2022. PMID: 35395649.
. Cognitive predictors of social adjustment in pediatric brain tumor survivors treated with photon versus proton radiation therapy. Pediatr Blood Cancer 69(6):e29645, 2022. e-Pub 2022. PMID: 35285129.
. Cognitive and Imaging Differences After Proton and Photon Whole Brain Irradiation in a Preclinical Model. Int J Radiat Oncol Biol Phys 112(2):554-564, 2022. e-Pub 2021. PMID: 34509550.
. Brain Radiation Necrosis Outside the Target Volume After Proton Radiation Therapy: Analyses of Multiparametric Imaging and Proton Biologic Effectiveness. Adv Radiat Oncol 7(6):101044, 2022. e-Pub 2022. PMID: 36420203.
. A Prospective Phase II Randomized Trial of Proton Radiotherapy vs. Intensity Modulated Radiotherapy for Patients with Newly Diagnosed Glioblastoma. Neuro Oncol 23(8):1337-1347, 2021. e-Pub 2021. PMID: 33647972.
. Treatment age and neurocognitive outcomes following proton beam radiotherapy for pediatric low- and intermediate-grade gliomas. Pediatr Blood Cancer 68(8):e29096, 2021. e-Pub 2021. PMID: 34019329.
. Overall survival and secondary malignant neoplasms in children receiving passively scattered proton or photon craniospinal irradiation for medulloblastoma. Cancer. e-Pub 2021. PMID: 34254296.
. Cell lines of the same anatomic site and histologic type show large variability in intrinsic radiosensitivity and relative biological effectiveness to protons and carbon ions. Med Phys 48(6):3243-3261, 2021. e-Pub 2021. PMID: 33837540.
. Cognitive Risk in Survivors of Pediatric Brain Tumors. J Clin Oncol 39(16):1718-1726, 2021. e-Pub 2021. PMID: 33886348.
. Long-term cognitive and academic outcomes among pediatric brain tumor survivors treated with proton versus photon radiotherapy. Pediatr Blood Cancer:e29125. e-Pub 2021. PMID: 34114294.
. A framework for voxel-based assessment of biological effect after proton radiotherapy in pediatric brain cancer patients using multi-modal imaging. Med Phys. e-Pub 2021. PMID: 34021597.
. Salivary and Dental Complications in Childhood Cancer Survivors Treated With Radiation Therapy to the Head and Neck: A Pediatric Normal Tissue Effects in the Clinic (PENTEC) Comprehensive Review. Int J Radiat Oncol Biol Phys. e-Pub 2021. PMID: 34074567.
. NF-��B Blockade by NEMO Binding Domain Peptide Ameliorates Inflammation and Neurobehavioral Sequelae After Cranial Radiation Therapy in Juvenile Mice. Int J Radiat Oncol Biol Phys 109(5):1508-1520, 2021. e-Pub 2020. PMID: 33307152.
. Early Radiotherapy Preserves Vision in Sporadic Optic Pathway Glioma. Cancer. e-Pub 2021. PMID: 33739455.
. Disease Control and Patterns of Failure After Proton Beam Therapy for Rhabdomyosarcoma. Int J Radiat Oncol Biol Phys 109(3):718-725, 2021. PMID: 33516439.
. Young Adult Populations Face yet another Barrier to Care with Insurers: Limited Access to Proton Therapy. Int J Radiat Oncol Biol Phys. e-Pub 2021. PMID: 33677051.
. Observed-to-expected incidence ratios of second malignant neoplasms after radiation therapy for medulloblastoma: A surveillance, epidemiology, and end results analysis. Cancer. e-Pub 2021. PMID: 33721338.
. Referral Patterns and Treatment Delays in Medulloblastoma: A Large Academic Proton Center Experience. Int J Part Ther 7(3):1-10, 2021. e-Pub 2020. PMID: 33604411.
. Proton Radiotherapy to Reduce Late Complications in Childhood Head and Neck Cancers. Int J Part Ther 8(1):155-167, 2021. e-Pub 2021. PMID: 34285943.
. Phase II trial of proton therapy versus photon IMRT for GBM: secondary analysis comparison of progression-free survival between RANO versus clinical assessment. Neurooncol Adv 3(1):vdab073, 2021. e-Pub 2021. PMID: 34337411.
. Oxygen depletion in FLASH ultra-high-dose-rate radiotherapy: A molecular dynamics simulation. Med Phys 47(12):6551-6561, 2020. e-Pub 2020. PMID: 33089504.
. Mapping the Relative Biological Effectiveness of Proton, Helium and Carbon Ions with High-Throughput Techniques. Cancers (Basel) 12(12), 2020. e-Pub 2020. PMID: 33291477.
. Roadmap: proton therapy physics and biology. Phys Med Biol. e-Pub 2020. PMID: 33227715.
. Author Correction: Exploring the advantages of intensity-modulated proton therapy: experimental validation of biological effects using two different beam intensity-modulation patterns. Sci Rep 10(1):19101, 2020. e-Pub 2020. PMID: 33127998.
. Relationship between treatment center case volume and survival for localized Ewing sarcoma: The role of radiotherapy timing. Pediatr Blood Cancer:e28685. e-Pub 2020. PMID: 32881378.
. Development of second primary tumors and outcomes in medulloblastoma by treatment modality: A Surveillance, Epidemiology, and End Results analysis. Pediatr Blood Cancer 67(8):e28373, 2020. e-Pub 2020. PMID: 32453481.
. A simple model for calculating relative biological effectiveness of X-rays and gamma radiation in cell survival. Br J Radiol 93(1112):20190949, 2020. e-Pub 2020. PMID: 32464080.
. Proton Therapy Reduces the Likelihood of High-Grade Radiation-Induced Lymphopenia in Glioblastoma Patients: Phase II Randomized Study of Protons vs. Photons. Neuro Oncol. e-Pub 2020. PMID: 32750703.
. A New Approach to Modeling the Microdosimetry of Proton Therapy Beams. Med Phys 47(7):3184-3190, 2020. e-Pub 2020. PMID: 32249429.
. Reply to S.A. Milgrom et al. J Clin Oncol 38(19):2212-2213, 2020. e-Pub 2020. PMID: 32374644.
. Radiation for Glioblastoma in the Era of Coronavirus Disease 2019 (COVID-19): Patient Selection and Hypofractionation to Maximize Benefit and Minimize Risk. Adv Radiat Oncol 5(4):743-745, 2020. e-Pub 2020. PMID: 32775785.
. A biological effect-guided optimization approach using beam distal-edge avoidance for intensity-modulated proton therapy. Med Phys. e-Pub 2020. PMID: 32557747.
Zhang D, Zhou W, Lam TT, Li V, Duman JG, Dougherty PM, Grosshans DR. Cranial irradiation induces axon initial segment dysfunction and neuronal injury in the prefrontal cortex and impairs hippocampal coupling. Neurooncol Adv. e-Pub 2020. PMID: 32642710.
. Premorbid functioning as a predictor of outcome in pediatric brain tumor: An initial examination of the normalcy assumption. Pediatr Blood Cancer 67(4):e28135, 2020. e-Pub 2019. PMID: 31886612.
. Hippocampal Avoidance During Whole-Brain Radiotherapy Plus Memantine for Patients With Brain Metastases: Phase III Trial NRG Oncology CC001. J Clin Oncol 38(10):1019-1029, 2020. e-Pub 2020. PMID: 32058845.
. Cognitive mediators of adaptive functioning outcomes in survivors of pediatric brain tumors treated with proton radiotherapy. Pediatr Blood Cancer 67(2):e28064, 2020. e-Pub 2019. PMID: 31736188.
. Superior Intellectual Outcomes After Proton Radiotherapy Compared With Photon Radiotherapy for Pediatric Medulloblastoma. J Clin Oncol 38(5):454-461, 2020. e-Pub 2019. PMID: 31774710.
. Salvage Therapy for Local Progression following Definitive Therapy for Skull Base Chordomas: Is There a Role of Stereotactic Radiosurgery?. J Neurol Surg B Skull Base 81(1):97-106, 2020. e-Pub 2019. PMID: 32021756.
. Exploring the advantages of intensity-modulated proton therapy: experimental validation of biological effects using two different beam intensity-modulation patterns. Sci Rep 10(1):3199, 2020. e-Pub 2020. PMID: 32081928.
. A DNA damage multi-scale model for NTCP in proton and hadron therapy. Med Phys 47(4). e-Pub 2020. PMID: 31955444.
Bright SJ, Flint DB, Chakraborty S, McFadden CH, Yoon DS, Bronk L, Titt U, Mohan R, Grosshans DR, Sumazin P, Shaitelman SF, Asaithamby A, Sawakuchi GO. Non-homologous end joining is more important than proton linear energy transfer in dictating cell death. Int J Radiat Oncol Biol Phys 105(5):1119-1125, 2019. e-Pub 2019. PMID: 31425731.
Wu RY, Liu AY, Yang J, Williamson TD, Wisdom PG, Bronk L, Gao S, Grosshans DR, Fuller DC, Gunn GB, Zhu XR, Frank SJ. Evaluation of the accuracy of deformable image registration on MRI with a physical phantom. J Appl Clin Med Phys. e-Pub 2019. PMID: 31808307.
. Patterns of failure and toxicity profile following proton beam therapy for pediatric bladder and prostate rhabdomyosarcoma. Pediatr Blood Cancer 66(11):e27952, 2019. e-Pub 2019. PMID: 31397065.
. Systematic microdosimetric data for protons of therapeutic energies calculated with Geant4-DNA. Phys Med Biol 64(21), 2019. e-Pub 2019. PMID: 31553958.
. Adaptive functioning in pediatric brain tumor survivors: An examination of ethnicity and socioeconomic status. Pediatr Blood Cancer 66(9):e27800, 2019. e-Pub 2019. PMID: 31134755.
. Efficacy of proton therapy in children with high-risk and locally recurrent neuroblastoma. Pediatr Blood Cancer 66(8):e27786, 2019. e-Pub 2019. PMID: 31050179.
. Assembling the brain trust: the multidisciplinary imperative in neuro-oncology. Nat Rev Clin Oncol 16(8):521-522, 2019. e-Pub 2019. PMID: 31150024.
Darne CD, Alsanea F, Robertson D, Guan F, Pan T, Grosshans DR, Beddar S. A novel proton imaging system using a large-volume liquid scintillator: a preliminary study. Medical Physics, 2019. PMID: 32194988.
. The Insurance Approval Process for Proton Radiation Therapy: A Significant Barrier to Patient Care. Int J Radiat Oncol Biol Phys 104(4):724-733, 2019. e-Pub 2018. PMID: 30557675.
Darne CD; Alsanea F; Robertson D; Guan F; Pan T; Grosshans DR; Beddar S. A proton imaging system using a volumetric liquid scintillator: a preliminary study. Biomedical Physics & Engineering Express 5(4), 2019. e-Pub 2019. PMID: 32194988.
Tang TT, Zawaski JA, Kesler SR, Beamish CA, Reddick WE, Glass JO, Carney DH, Sabek OM, Grosshans DR, Gaber MW. A comprehensive preclinical assessment of late-term imaging markers of radiation-induced brain injury. Neurooncol Adv. e-Pub 2019. PMID: 31608330.
Newpower M, Patel D, Bronk L, Guan F, Chaudhary P, McMahon SJ, Prise KM, Schettino G, Grosshans DR, Mohan R. Using the Proton Energy Spectrum and Microdosimetry To Model Proton Relative Biological Effectiveness. Int J Radiat Oncol Biol Phys 104(2):316-324, 2019. e-Pub 2019. PMID: 30731186.
. Prospective, Longitudinal Comparison of Neurocognitive Change in Pediatric Brain Tumor Patients Treated with Proton Radiotherapy versus Surgery Only. Neuro Oncol 21(6):809-818, 2019. e-Pub 2019. PMID: 30753584.
. In Reply to Krishnatry and Manjali. Int J Radiat Oncol Biol Phys 104(2):468-469, 2019. PMID: 31047634.
. Timing of Local Therapy Impacts Survival in Ewing Sarcoma. Int J Radiat Oncol Biol Phys 104(1):127-136, 2019. e-Pub 2018. PMID: 30593906.
. A Phase I/II Trial of Reirradiation for Diffuse Intrinsic Pontine Glioma. Int J Radiat Oncol Biol Phys 104(1):144-148, 2019. e-Pub 2019. PMID: 30610915.
. Increased Risk of Pseudoprogression among Pediatric Low-Grade Glioma Patients Treated with Proton versus Photon Radiotherapy. Neuro Oncol 21(5):686-695, 2019. e-Pub 2019. PMID: 30753704.
. Patterns of failure following proton beam therapy for head and neck rhabdomyosarcoma. Radiother Oncol 134:143-150, 2019. e-Pub 2019. PMID: 31005208.
Buszek SM, Ikner S, Wiedermann L, Wang J, McAleer MF, Grosshans DR, de la Cruz Paulino A, McGovern SL, Chung C. Safety and Feasibility of Magnetic Resonance Imaging Simulation for Radiation Treatment Planning in Pediatric Patients: A Single Institution Experience. Advances in Radiation Oncology 4(2):362-366, 2019. e-Pub 2018. PMID: 31011682.
. Report of the AAPM TG-256 on the relative biological effectiveness of proton beams in radiation therapy. Med Phys 46(3):e53-e78, 2019. e-Pub 2019. PMID: 30661238.
Abolfath R, Helo Y, Bronk L, Carabe A, Grosshans DR, Mohan R. Renormalization of radiobiological response functions by energy loss fluctuations and complexities in chromosome aberration induction: deactivation theory for proton therapy from cells to tumor control. The European Physical Journal D 73(64), 2019.
Durante M, Paganetti H, Pompos A, Kry SF, Wu X, Grosshans DR. Report of a National Cancer Institute Special Panel: Characterization of the Physical Parameters of Particle Beams for Biological Research. Medical Physics 46(2):e37-e52, 2019. e-Pub 2018. PMID: 30506898.
. Radiation for ETMR: Literature review and case series of patients treated with proton therapy. Clin Transl Radiat Oncol 15:31-37, 2019. e-Pub 2018. PMID: 30582019.
. Differences in patterns of care and outcomes between grade II and grade III molecularly defined 1p19q co-deleted gliomas. Clin Transl Radiat Oncol 15:46-52, 2019. e-Pub 2018. PMID: 30656222.
Kohno R, Cao W, Yepes P, Bai X, Poenisch F, Grosshans DR, Akimoto T, Mohan R. Biological Dose Comparison between a Fixed RBE and a variable RBE in SFO and MFO IMPT with Various Multi-Beams for Brain Cancer. International Journal of Medical Physics,Clinical Engineering and Radiation Oncology 8(1):32-45, 2019.
. Reply to Comment on 'Linear energy transfer incorporated intensity modulated proton therapy optimization'. Phys Med Biol 64(5):058002, 2019. e-Pub 2019. PMID: 30811349.
Bai X, Lim G, Grosshans D, Mohan R, Cao W.. Robust optimization to reduce the impact of biological effect variation from physical uncertainties in intensity-modulated proton therapy. Phys Med Biol 64(2):1361-1365, 2019. PMID: 30523932.
. A mechanistic relative biological effectiveness model-based biological dose optimization for charged particle radiobiology studies. Phys Med Biol 64(1):015008, 2018. e-Pub 2018. PMID: 30523805.
Yepes P, Adair A, Frank SJ, Grosshans DR, Liao Z, Liu A, Mirkovic D, Poenisch F, Titt U, Wang Q, Mohan R. Fixed- versus Variable-RBE Computations for Intensity Modulated Proton Therapy. Adv Radiat Oncol 4(1):156-167, 2018. PMID: 30706024.
Yepes P, Adair A, Frank SJ, Grosshans DR, Liao Z, Liu A, Mirkovic D, Poenisch F, Titt U, Wang Q, Mohan R.. Fixed- versus Variable-RBE Computations for Intensity Modulated Proton Therapy. Adv Radiat Oncol 4(1):156-167, 2018.
. Radiotherapy Advances in Pediatric Neuro-Oncology. Bioengineering (Basel) 5(4), 2018. e-Pub 2018. PMID: 30400370.
. Endocrine Deficiency as a Function of Radiation Dose to the Hypothalamus and Pituitary in Pediatric and Young Adult Patients With Brain Tumors. J Clin Oncol 36(28):2854-2862, 2018. e-Pub 2018. PMID: 30118397.
Stoker J, Vora S, Patel A, Grosshans DR, Brown PD, Vern-Gross T, Bues M, Daniels T, Allred B, Uejo A, Kosiorek H, Bruso M, Keole S. Advantages of intensity modulated proton therapy during hippocampal. Physics and Imaging in Radiation Oncology 8(2018):28-32, 2018.
. Dose-volume metrics and their relation to memory performance in pediatric brain tumor patients: A preliminary study. Pediatr Blood Cancer 65(9):e27245, 2018. e-Pub 2018. PMID: 29856521.
Grosshans DR, Duman JG, Gaber MW, Sawakuchi G. Particle Radiation Induced Neurotoxicity in the Central Nervous System. International Journal of Particle Therapy, 2018.
Guan F, Geng C, Ma D, Bronk L, Kerr M, Li Y, Gates D, Kroger B, Sahoo N, Titt U, Grosshans DR, Mohan R. RBE Model-Based Biological Dose Optimization for Proton Radiobiology Studies. International Journal of Particle Therapy 5(1):160-171, 2018. PMID: 30338268.
. Multimodality Management of Recurrent Skull Base Chordomas: Factors Impacting Tumor Control and Disease-Specific Survival. Oper Neurosurg (Hagerstown) 15(2):131-143, 2018. e-Pub 2017. PMID: 29040778.
. Radiation induces age-dependent deficits in cortical synaptic plasticity. Neuro Oncol 20(9):1207-1214, 2018. e-Pub 2018. PMID: 29660023.
. Ototoxicity and cochlear sparing in children with medulloblastoma: Proton vs. photon radiotherapy. Radiother Oncol 128(1):128-132, 2018. e-Pub 2018. PMID: 29373195.
. Chemotherapy Plus Proton or Photon Radiation on a Trial. Int J Radiat Oncol Biol Phys 101(3):518-519, 2018. PMID: 29893270.
. Toward A variable RBE for proton beam therapy. Radiother Oncol 128(1):68-75, 2018. e-Pub 2018. PMID: 29910006.
. Regional Nodal Control for Head and Neck Alveolar Rhabdomyosarcoma. Int J Radiat Oncol Biol Phys 101(1):169-176, 2018. e-Pub 2018. PMID: 29477293.
. National Cancer Institute Workshop on Proton Therapy for Children: Considerations Regarding Brainstem Injury. Int J Radiat Oncol Biol Phys 101(1):152-168, 2018. PMID: 29619963.
. Radiation-induced cognitive toxicity: Pathophysiology and interventions to reduce toxicity in adults. Neuro Oncol 20(5):597-607, 2018. e-Pub 2017. PMID: 29045710.
. Memantine prevents acute radiation-induced toxicities at hippocampal excitatory synapses. Neuro Oncol 20(5):655-665, 2018. e-Pub 2017. PMID: 29112734.
. Erratum: "Analysis of the track- and dose-averaged LET and LET spectra in proton therapy using the geant4 Monte Carlo code" [Med. Phys. 42 (11), page range 6234-6247(2015)]. Med Phys 45(3):1302, 2018. e-Pub 2018. PMID: 29527697.
. Erratum: "Monte Carlo simulations of3He ion physical characteristics in a water phantom and evaluation of radiobiological effectiveness" [Med. Phys. 43 (2), page range 761-776(2016)]. Med Phys 45(3):1301, 2018. e-Pub 2018. PMID: 29527699.
. Average stopping powers for electron and photon sources for radiobiological modeling and microdosimetric applications. Phys Med Biol 63(5):055007, 2018. e-Pub 2018. PMID: 29411712.
. Proceedings of the National Cancer Institute Workshop on Charged Particle Radiobiology. Int J Radiat Oncol Biol Phys 100(4):816-831, 2018. e-Pub 2017. PMID: 29485053.
. Comparison of Monte Carlo and analytical dose computations for intensity modulated proton therapy. Phys Med Biol 63(4):045003, 2018. e-Pub 2018. PMID: 29339570.
Bronk JK, Guha-Thakurta N, Allen PK, Mahajan A, Grosshans DR, McGovern SL. Analysis of pseudoprogression after proton or photon therapy of 99 patients with low grade and anaplastic glioma. Clin Transl Radiat Oncol 9:30-34, 2018. PMID: 29594248.
. Linear energy transfer incorporated intensity modulated proton therapy optimization. Phys Med Biol 63(1), 2017. e-Pub 2017. PMID: 29131808.
. Synchrotron-Based Pencil Beam Scanning Nozzle with an Integrated Mini-Ridge Filter: A Dosimetric Study to Optimize Treatment Delivery. Cancers (Basel) 9(12), 2017. e-Pub 2017. PMID: 29236051.
. Radiobiological issues in proton therapy. Acta Oncol 56(11):1-7, 2017. e-Pub 2017. PMID: 28826292.
. Optimization of Monte Carlo particle transport parameters and validation of a novel high throughput experimental setup to measure the biological effects of particle beams. Med Phys 44(11):6061-6073, 2017. e-Pub 2017. PMID: 28880368.
Kohno R, Cao W, Yepes P, Bai X, Poenisch F, Grosshans DR, Akimoto T, Mohan R. Dose Comparison between Eclipse Dose Calculation and Fast Dose Calculator in Single- and Multi-Field Optimization Intensity-Modulated Proton Therapy Plans with Various Multi-Beams for Brain Cancer. International Journal of Medical Physics, Clinical Engineering and Radiation Oncology. e-Pub 2017.
Patel D, Bronk L, Guan F, Peeler C, Brons S, Dokic I, Abdollahi A, Rittmueller C, J?kel O, Grosshans DR, Mohan R, Titt U. Optimization of Monte Carlo particle transport parameters and validation of a novel high throughput experimental setup to measure the biological effects of particle beams. Medical Physics 44(11):6061-6073, 2017. PMID: 28880368.
. A new formalism for modelling parameters �� and �� of the linear quadratic model of cell survival for hadron therapy. Phys Med Biol 62(20):8041-8059, 2017. e-Pub 2017. PMID: 28832343.
. Multimodality Treatment of Skull Base Chondrosarcomas: The Role of Histology Specific Treatment Protocols. Neurosurgery 81(3):520-530, 2017. PMID: 28368506.
. A model for relative biological effectiveness of therapeutic proton beams based on a global fit of cell survival data. Sci Rep 7(1):8340, 2017. e-Pub 2017. PMID: 28827691.
. Attention, processing speed, and executive functioning in pediatric brain tumor survivors treated with proton beam radiation therapy. Radiother Oncol 124(1):89-97, 2017. e-Pub 2017. PMID: 28655455.
. The role of image-guided intensity modulated proton therapy in glioma. Neuro Oncol 19(suppl_2):ii30-ii37, 2017. PMID: 28380636.
Hou P, Zhu KH, Park PC, Li H, Mahajan A, Grosshans DR. Proton Therapy for Juvenile Pilocytic Astrocytoma: Quantifying Treatment Responses by Magnetic Resonance Diffusion Tensor Imaging. International Journal of Particle Therapy 3(3):414-420, 2017.
. The Potential of Heavy-Ion Therapy to Improve Outcomes for Locally Advanced Non-Small Cell Lung Cancer. Front Oncol 7:201, 2017. e-Pub 2017. PMID: 28929085.
. Clinical evidence of variable proton biological effectiveness in pediatric patients treated for ependymoma. Radiother Oncol 121(3):395-401, 2016. e-Pub 2016. PMID: 27863964.
. Proton therapy - Present and future. Adv Drug Deliv Rev. e-Pub 2016. PMID: 27919760.
. Spot scanning proton therapy minimizes neutron dose in the setting of radiation therapy administered during pregnancy. J Appl Clin Med Phys 17(5):366-376, 2016. e-Pub 2016. PMID: 27685136.
Jiang S, Wang J, Li H, Liao L, Li Y, Wang X, Yang Y, Zhu RX, Sahoo N, Gillin MT, Hojo Y, Sun J, Chang JY, Liao Z, Grosshans DR, Frank SJ, Zhang X. Novel Hybrid Scattering- and Scanning-Beam Proton Therapy Approach. International Journal of Particle Therapy 3(1):37-50, 2016.
. Impact of heart and lung dose on early survival in patients with non-small cell lung cancer treated with chemoradiation. Radiother Oncol 119(3):495-500, 2016. e-Pub 2016. PMID: 27189523.
. A multi-institutional pilot survey of anesthesia practices during proton radiation therapy. Pract Radiat Oncol 6(3):155-9, 2016. e-Pub 2015. PMID: 26725965.
Agarwal A, Thaker NG, Tawk B, Allen PK, Grosshans DR, Herzog CE, Gombos DS, Mahajan A. The Evolution of Radiation Therapy for Retinoblastoma: The MD Anderson Cancer Center Experience. International Journal of Particle Therapy 4(4):490-498, 2016.
. Comparing Intelligence Quotient Change After Treatment With Proton Versus Photon Radiation Therapy for Pediatric Brain Tumors. J Clin Oncol 34(10):1043-9, 2016. e-Pub 2016. PMID: 26811522.
. Proton therapy for paediatric medulloblastoma. Lancet Oncol 17(3):258-9, 2016. e-Pub 2016. PMID: 26830376.
. A Retrospective Evaluation of the Benefit of Referring Pediatric Cancer Patients to an External Proton Therapy Center. Pediatr Blood Cancer 63(2):262-269, 2016. e-Pub 2015. PMID: 26397177.
. Monte Carlo simulations of ?He ion physical characteristics in a water phantom and evaluation of radiobiological effectiveness. Med Phys 43(2):761-76, 2016. PMID: 26843239.
. Analysis of the track- and dose-averaged LET and LET spectra in proton therapy using the geant4 Monte Carlo code. Med Phys 42(11):6234, 2015. PMID: 26520716.
. Proton versus conventional radiotherapy for pediatric salivary gland tumors: Acute toxicity and dosimetric characteristics. Radiother Oncol 116(2):309-15, 2015. e-Pub 2015. PMID: 26232128.
. Post-operative proton therapy for chordomas and chondrosarcomas of the spine: Adjuvant vs. salvage radiation therapy. Spine (Phila Pa 1976) 40(8):544-9, 2015. e-Pub 2015. PMID: 25627289.
. Spatial mapping of the biologic effectiveness of scanned particle beams: towards biologically optimized particle therapy. Sci Rep 5:9850, 2015. e-Pub 2015. PMID: 25984967.
. Outcomes and Acute Toxicities of Proton Therapy for Pediatric Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System. Int J Radiat Oncol Biol Phys 90(5):1143-52, 2014. e-Pub 2014. PMID: 25311260.
. Spot Scanning Proton Therapy for Malignancies of the Base of Skull: Treatment Planning, Acute Toxicities, and Preliminary Clinical Outcomes. Int J Radiat Oncol Biol Phys 90(3):540-6, 2014. e-Pub 2014. PMID: 25304948.
. Preliminary Results of a Phase II Trial of Proton Radiotherapy for Pediatric Rhabdomyosarcoma. J Clin Oncol 32(33):3762-70, 2014. e-Pub 2014. PMID: 25332253.
. Intensity modulated proton therapy for craniospinal irradiation: organ-at-risk exposure and a low-gradient junctioning technique. Int J Radiat Oncol Biol Phys 90(3):637-44, 2014. e-Pub 2014. PMID: 25194667.
. Proton Beam Therapy Versus Conformal Photon Radiation Therapy for Childhood Craniopharyngioma: Multi-institutional Analysis of Outcomes, Cyst Dynamics, and Toxicity. Int J Radiat Oncol Biol Phys 90(2):354-61, 2014. e-Pub 2014. PMID: 25052561.
Ladra MM, Samantha K. Edgington SK, Szymonifka J, Mahajan A, Khan F, Moteabbed M, Friedmann AM, MacDonald SM, Grosshans DR, Tarbell NJ, Yock TI. A Dosimetric Comparison of Proton Radiotherapy and IMRT in Pediatric RMS Patients Enrolled on a Phase II Proton Study. Radiotherapy Oncology 113(1):77-83, 2014. PMID: 25443861.
. Prospective exploratory analysis of cardiac biomarkers and electrocardiogram abnormalities in patients receiving thoracic radiation therapy with high-dose heart exposure. J Thorac Oncol 9(10):1554-60, 2014. PMID: 25521400.
Zhu, XR, Poenisch F, Wu RY, Taylor MB, Sahoo N, Zhang X, Lee AK, Chang EL, Choi S, Pugh T, Frank SJ, Palmer MB, Amin MV, Gillin MT, Mahajan A, Grosshans DR. A Single-Field Integrated Boost Technique for Spot Scanning Proton Therapy. Radiation Oncology, 2014. PMID: 25212571.
. Molecular Imaging Detects Impairment in the Retrograde Axonal Transport Mechanism After Radiation-Induced Spinal Cord Injury. Mol Imaging Biol 16(4):504-10, 2014. e-Pub 2014. PMID: 24395625.
. In-beam PET imaging for on-line adaptive proton therapy: An initial phantom study. Phys Med Biol 59(13):3373-88, 2014. e-Pub 2014. PMID: 24874943.
. Is there an impact of heart exposure on the incidence of radiation pneumonitis? Analysis of data from a large clinical cohort. Acta Oncol 53(5):590-6, 2014. e-Pub 2013. PMID: 23992110.
. Non-invasive anesthesia for children undergoing proton radiation therapy. Radiother Oncol 111(1):30-4, 2014. e-Pub 2014. PMID: 24560754.
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